RABS – Restricted Access Barrier System

SKAN offers professional support to ensure that your equipment is operating at maximum productivity and reliability. The development of comprehensive maintenance programs and services covering all aspects of SKAN equipment was inspired by the decades of hands-on experience of SKANs experts.

Our certified technicians perform precise recalibrations and repairs as well as modification requests on site, to maintain the qualified status of your equipment. Also microbiological recalibrations to check the effectiveness of the decontamination process and to guarantee the safety of the workplace, can be realized professionally and reliably.

Besides the isolator support, SKAN completes its comprehensive LifeCycle Support portfolio with a 24-hour emergency service hotline. Our service hotline is staffed by a dedicated team of specialists who provide direct and efficient support for all types of troubleshooting.

Thanks to state-of-the-art equipment and in-depth expertise, SKAN Stein AG is the right partner to perform tests and simulations of your machines and processes. In addition to strength calculations (FEM) of containers and pedestals and calculations of air flows (CFD), the experienced engineering team also takes care of the design and implementation of individually designed tests. Our experienced technicians are able to carry out various tests and simulations remotely at SKANs facilities. With SKAN Stein AG, you can count on the best possible all-round support for your project.

Isolator systems and integrated technology are becoming increasingly complex. Individual plants and isolators often combine a variety of process systems from different manufacturers. Due to the integration of different systems, even the smallest detail can be crucial to the successful operation and validation of the entire system.

SKAN offers its customers the possibility of realistic mockup studies. These studies have a significant impact on the design phase of an isolator process by pre-designing the entire system according to reality conditions in a model. The mockups are always developed in close cooperation between SKAN, the customer and the supplier to meet the individual requirements.


Design individual previews with SKAN Mockups:

• The special CAM cardboard system enables dimensionally accurate production
• The cardboard system enables simple and quick design adjustments
• The three-dimensional structure conveys a realistic feeling and supports a more precise idea of the implementation
• The glove openings are easily adjustable on all sides
• Thanks to 3D printing, complete components can also be displayed

Understanding and controlling airflow in aseptic isolators is crucial for ensuring a sterile environment, but it’s often complex due to various factors affecting the flow dynamics.

Computational Fluid Dynamics (CFD), a specialized area within fluid mechanics, uses numerical algorithms to model and simulate fluid flows. Employing CFD allows for a detailed analysis of airflow patterns inside isolators, eliminating the need for costly and time-consuming experiments like smoke studies.

At SKAN, we offer CFD services designed to address your engineering requirements with precision and efficiency.

Our CFD services include:


• High-fidelity simulations employing state-of-the-art techniques for predicting airflow patterns in isolators
• Rigorous risk assessment analysis for contamination using detailed particle tracking
• Comprehensive reports with visualizations to facilitate decision-making and reduce design risks
• Performing sensitivity analysis on desired parameters across critical sections
• Utilizing nearly real-time airflow simulation to optimize designs by exploring various geometries within isolator or filling line sections

In addition to the successful operation of isolators and plants, SKAN also supports its customers with SKANalytix in the area of data analysis, data evaluation and documentation. To meet the different requirements SKAN offers the analytical service packages active, clean and persist.
The services include the analysis of the cleanability of isolators, the evaluation and development of individual cleaning processes, the determination of suitable packaging materials and the H₂O₂ influence on sterility tests.

It goes without saying that we follow the standards of “Good Manufacturing Practice” (GMP) as well as common standards and guidelines both in the execution and documentation of services.