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Technician in a blue cleanroom suit operating a SKAN isolator machine using glove ports in a sterile environment.
Transfer systems

mat

The smallest isolator for fast material transfers

Transfer type
Material
Customization level
Modular configuration
mat at a glance

Efficient surface decontamination for materials

  • Maximum safety

    Fully automated processes reduce manual interventions and associated risks

  • Regulatory compliance

    Complies with Annex 1 and all relevant GMP requirements

  • Efficient transfers

    Short transfer paths and times thanks to close proximity to the filling line

  • Compact design

    Only 1.5 m² footprint for easy integration, even in confined production areas

  • Independent operation

    Standalone solution without external HVAC connection thanks to the nanox catalyst

  • Flexible integration

    Compatible with a wide range of materials, container sizes, and production layouts

  • Easy handling

    Floor-level loading solutions and a large glass door for simple operation

  • Individual configuration

    Modular design with numerous shelving solutions and options

Application

Safe transfer of materials and containers into isolator filling lines

  • For the preparation of filling processes

    Decontamination and transfer of tools, consumables, and other items required for the aseptic or aseptic-toxic filling operations.

  • For the decontamination of heat-sensitive materials

    Decontamination using hydrogen peroxide (H₂O₂) for heat-sensitive materials that cannot be autoclaved, without compromising product quality.

Technician in a blue cleanroom suit working with a large stainless steel transfer port in a sterile laboratory environment.
Process

Efficient transfer from Grade C or Grade D into the Grade A working chamber

  • 1

    Loading

    Materials are loaded into the mat isolator, which is typically positioned close to a filling line in a Grade C or D cleanroom.

  • 2

    Decontamination

    Fully automated cycle using H₂O₂ via skanfog micro-nebulization technology. Efficient process within 30–45 minutes, including leak testing.

  • 3

    Transfer out

    After validated decontamination, transfer via Rapid Transfer Port (RTP) containers. The materials are then introduced into the filling line.

  • 4

    H₂O₂ neutralization

    The nanox catalyst fully decomposes H₂O₂ after decontamination. No HVAC connection is required, as the exhaust air can be safely returned directly to the room.

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Product highlights

Efficient, safe, fast – benefits that make a difference in operation

  • Close-up of a circular white transfer port with a yellow gasket, integrated into a brushed stainless steel surface.

    Automated safety

    A high degree of automation and standardized processes minimize risks in the transfer process and simplify risk assessment.

  • Time efficiency

    Cycle times of only 30–45 minutes (for empty chambers, without RTPs) accelerate material flow and increase overall production efficiency.

  • Operational flexibility

    The process can be adapted to different transfer types, materials, and monitoring requirements without compromising product integrity.

Regulatory requirements

Standardized processes for regulatory-compliant transfers

  • Annex 1-compliant

    Supports microbiological and particulate monitoring in accordance with Annex 1.

  • GMP standards

    Enables GMP-compliant transfers according to EU GMP Grade A (ISO 5).

  • Validation-friendly

    Automated cycles and SOP-based operation reduce validation effort.

MAT material transfer by SKAN: Person in full cleanroom attire handling a cylindrical stainless steel machine component in a laboratory setting.
MAT by SKAN.
MAT by SKAN.

Technical specifications

  • Footprint

    Approx. 1.5 m² (approx. 16 ft²)

  • Weight

    Approx. 800 kg

  • Working chamber

    EU-GMP Grade A (ISO 5)

  • Decontamination

    > 6-log decontamination via skanfog H₂O₂ micro-nebulization

  • Airflow

    Unidirectional, without recirculation

  • Exhaust air

    Directly into the room thanks to SKAN nanox catalyst for rapid decomposition of hydrogen peroxide after decontamination (single-pass reduction of H₂O₂ to < 0.1 ppm)

  • RTP for solids

    Up to size 350

  • AT-Port

    For aseptic liquid transfers

  • Glove test device

    With position control

  • Shelving installation

    Available on request

  • Room monitoring

    H₂O₂ TLV sensor

  • Chamber monitoring

    H₂O₂ sensors

  • Microbial and particulate monitoring

    In accordance with Annex 1

  • Control

    PLC-based system; Siemens or Allen Bradley

  • User interface

    18.5” HMI (customizable)

  • SCADA

    System for monitoring and control, GMP-compliant and 21 CFR Part 11-ready

FAQs

  • mat provides validated decontamination and standardized cycles, minimizing the risk of manual interventions. This supports compliance with the tightened Annex 1 requirements for Contamination Control Strategy (CCS) and aseptic material transfer.

  • Unlike conventional airlocks, mat is fully isolated and operates with automated H₂O₂ cycles. This makes decontamination reproducible, faster, and safer with significantly fewer manual interventions.

  • By reducing transfer paths and times and accelerating decontamination, filling line downtime is reduced. In many cases, mat shortens the material preparation process from several hours to less than one hour, a measurable efficiency gain in routine operation.

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