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A stainless steel AT-Port™ on an industrial panel with a mechanical locking lever assembly positioned nearby.
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Transfer systems

AT-Port System

Safe transfer of liquids between containment areas

Transfer type
Liquids
Customization level
Standardized
AT-Port System at a glance

Safest liquid transfers between isolator and cleanroom

  • Integrity and assurance

    Maintains Grade A conditions throughout the transfer process

  • For aseptic and toxic processes

    Supports both aseptic and high-containment transfers

  • Broad use cases

    Compatible with any process using the connector single-use system

  • Flexible environment

    Can be integrated into various barrier systems

  • Fast operation

    Aseptic connections can be established within seconds, streamlining critical transfer steps

  • Multiple uses within the same batch

    Each connector single-use system supports up to five validated connections and disconnections

  • Enhanced safety

    Integrated interlocks ensure safe operation

  • Quality assurance

    Each connector single-use system undergoes 100% air leak testing to confirm integrity

Application

Liquid transfers for pharmaceutical processes

  • For pharmaceutical filling

    Designed for liquid transfer in environments with the highest sterility requirements, including transfers between ISO 8 and ISO 5 classified areas.

  • For biotech and ATMP manufacturing

    The transfer of advanced products such as ATMPs, including cell and gene therapies, can also be reliably handled using the AT-Port system.

  • For integration into isolators

    The AT-Port system can be integrated into isolators and Restricted Access Barrier Systems (RABS). It is compatible with all SKAN isolators.

  • For high-containment applications

    Enables safe liquid transfer when handling hazardous or highly potent substances, protecting both operators and the product.

Close-up of an aseptic white nozzle being connected to a stainless steel AT-Port™ with mechanical alignment markers - by SKAN AG Switzerland.
Pocess

Aseptic liquid transfer with AT-Port System

  • 1

    Connect to bulk container

    Connector single-use system is attached to the bulk container and locked into the external wall port between containment zones.

  • 2

    Secure connector cover

    From the higher-grade area (e.g., ISO 5), the connector cover is secured inside the internal port. Rotation opens the beta part under controlled conditions.

  • 3

    Uncover connecting tube

    The connecting tube is safely exposed only inside the higher-grade chamber, preserving aseptic integrity.

  • 4

    Aseptic connection and transfer

    Sterile connection is established, and liquid transfer begins immediately. The entire sequence is fast and precisely controlled, minimizing contamination risk.

Product highlights

Safe transfer processes as key for contamination control

  • Close-up of a stainless steel AT-Port™ connection with a white tube attached, showing "START" and "STOP" markings - by SKAN.

    Grade A continuity

    Aseptic integrity is maintained throughout the entire process, ensuring sterility.

  • A gloved hand inserting a white aseptic transfer nozzle into a stainless steel port with locking latches.

    Built-in safety

    Interlock mechanisms prevent accidental exposure or improper operation, ensuring protection even in high-containment use. The beta part cannot be opened without the connector single-use system (SUS) in place, and the SUS cannot be removed unless the beta part is closed.

  • Close-up of a white aseptic connector being aligned with a stainless steel AT-Port™ on an industrial surface.

    Broad versatility

    Applicable in sterile pharmaceutical operations and when handling highly potent or hazardous substances.

AT-Port System - Safe transfer of liquids between containment areas.
AT-Port System - Safe transfer of liquids between containment areas.

Technical specifications

  • External port

    Stainless steel AISI 316L, Ø 159 mm, thickness 24 mm

  • Internal port

    Stainless steel AISI 316L + PEEK, 200 mm length, 110 mm radius (claimed)

  • For stainless steel walls

    2–6 mm, up to 7 mm per specification

  • Details

    Gamma-irradiated, validated for up to 5 connections/disconnections

  • Material

    PBT Celanex grade 2402, animal-free

  • Size

    72 mm length, Ø 55 mm

  • Connections

    3/8” hose barb (external), 3/8” or 5/16” tube (internal)

  • Details

    Gamma-irradiated

  • Tubing

    C-Flex® (I.D. 3.2 mm, O.D. 6.4 mm, 900 mm length)

  • Termination

    Luer lock, only exposed inside isolator

  • Materials

    PBT, C-Flex®, PVDF/Kynar®, animal-free 

FAQs

  • The AT-Port enables aseptic or high-containment liquid transfer across containment zones (e.g., ISO 8 to ISO 5), preventing sterility and toxicity breaches.

  • The alpha-beta design maintains Grade A conditions. Safety interlocks prevent accidental disconnection or exposure. Each connector single-use system is leak-tested for integrity.

  • Yes, each connector single-use system allows up to five validated connections with the AT-Port. The system supports both conventional and single-use setups and is compatible with AT-Connect and AT-Connector.

  • Yes. SKAN offers full life-cycle support, including requalification, spare parts, troubleshooting hotline, and engineering services such as simulations and customized solutions.

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