{"id":54091,"date":"2025-05-22T09:31:00","date_gmt":"2025-05-22T07:31:00","guid":{"rendered":"https:\/\/skan.clients.ideeal.ch\/?post_type=produkte&#038;p=54091"},"modified":"2026-05-13T22:28:59","modified_gmt":"2026-05-13T20:28:59","slug":"at-closed-vial","status":"publish","type":"produkte","link":"https:\/\/skan.com\/en\/products\/pharma\/accessories\/at-closed-vial","title":{"rendered":"AT-Closed\u00a0Vial\u00ae"},"content":{"rendered":"    <section id=\"overview\" class=\"section-feature-grid pt-default pb-default\">\r\n        <div class=\"container\">\r\n                            <header class=\"entry-header any-b0\">\r\n                                            <h5>AT-Closed Vial\u00ae at a glance<\/h5>\r\n                                                                <h2>Innovative primary packaging for closed aseptic filling<\/h2>\r\n                                    <\/header>\r\n                                        <ul class=\"feature-grid-list list-reset\">\r\n                                                                                                <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Maximum product safety<\/h3>\r\n                                                                                                                <p>Closed filling process eliminates airborne contamination risks<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Validated container closure integrity (CCI) down to -196 \u00b0C<\/h3>\r\n                                                                                                                <p>Reliable integrity even under cryogenic conditions<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Reduced resource consumption<\/h3>\r\n                                                                                                                <p>No WFI consumption and reduced overfill requirements<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Low validation effort<\/h3>\r\n                                                                                                                <p>High process reliability enables fast validation of filling processes<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>High process efficiency<\/h3>\r\n                                                                                                                <p>Fast filling cycles combined with a zero-error process approach<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Scalable platform<\/h3>\r\n                                                                                                                <p>Compatible with AT filling solutions from development to commercial production<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Flexible barrier systems<\/h3>\r\n                                                                                                                <p>Compatible with AT filling solutions in BSC, RABS, and isolators<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"feature-grid-item any-b0\">\r\n                                    <figure class=\"icon\" aria-hidden=\"true\">\r\n                                                                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\"><rect x=\"0.5\" y=\"0.5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"M7 11.7308L10.5 15.5L17 8.5\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                            <\/figure>\r\n                                                                            <h3>Broad vial range<\/h3>\r\n                                                                                                                <p>Six sizes to cover various dosing requirements<\/p>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n    <\/section>\r\n\r\n\n\n    <section id=\"application\" class=\"section-image-text pt-default pb-default reverse default\">\r\n        <div class=\"container\">\r\n            <div class=\"entry-grid\">\r\n                                    <div class=\"text\">\r\n                        <div class=\"text-inner\">\r\n                                                            <h5>Application<\/h5>\r\n                                                                                        <h2>Closed vial technology for advanced biopharmaceutical processes<\/h2>\r\n                                                                                                                    <ul class=\"feature-list list-reset\">\r\n                                                                                                                                                                <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                            <figure>\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"24\" height=\"24\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/03\/pikto-zell-gentherapien.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                                                        <\/figure>\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>For ATMPs and cell and gene therapies<\/h3>\n<p>Designed for the aseptic filling of autologous and allogeneic therapies, viral vectors, and cell banks. Supports critical requirements such as limited processing times and high product sensitivity.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                                                                                                                        <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                            <figure>\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"24\" height=\"24\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/03\/Mikrobiologische-Bestimmung.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                                                        <\/figure>\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>For biotech companies, hospitals, and research institutions<\/h3>\n<p>Applicable from research through clinical phases to commercial manufacturing \u2013 compatible with manual, semi-automated, and fully automated AT filling lines.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                                                                                                                        <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                            <figure>\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"24\" height=\"24\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/03\/pikto-gefriergetrocknet.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                                                        <\/figure>\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>For cryogenic storage and intermediates<\/h3>\n<p>Enables safe storage and transport of products and GMP intermediates at temperatures down to -196 \u00b0C without loss of integrity or functionality.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                            <\/ul>\r\n                                                                                <\/div>\r\n                    <\/div>\r\n                                                    <div class=\"image\">\r\n                        <figure class=\"\">\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1474\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329-286x300.jpg 286w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329-975x1024.jpg 975w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329-768x806.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/at-closed-vial-at-adapt-usp5_resize-e1778664233329-357x375.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                                    <\/figure>\r\n                    <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/section>\r\n\n\n    <section  class=\"section-image-text pt-default pb-default default\">\r\n        <div class=\"container\">\r\n            <div class=\"entry-grid\">\r\n                                    <div class=\"text\">\r\n                        <div class=\"text-inner\">\r\n                                                            <h5>Fill Finish<\/h5>\r\n                                                                                        <h2>The AT-Closed Vial\u00ae ecosystem<\/h2>\r\n                                                        <p>The AT-Closed Vial<sup>\u00ae<\/sup> system enables a fully closed aseptic filling process.<\/p>\n<p>At its core is the AT-Closed Vial<sup>\u00ae<\/sup> as the primary packaging, combined with the AT-Cap as closure, complemented by suitable filling lines and the single-use system AT-Assembly for sterile liquid transfers.<\/p>\n<p>All components are fully aligned, ensuring a consistent, contamination-controlled, and scalable process.<\/p>\n                                                                                <\/div>\r\n                    <\/div>\r\n                                                    <div class=\"image\">\r\n                        <figure class=\"\">\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/at-closed-vial-filling-system-e1778585972383.jpg\" class=\"attachment-full size-full\" alt=\"\" \/>                                                    <\/figure>\r\n                    <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/section>\r\n\n\n    <section id=\"process\" class=\"section-process-element pt-default pb-default\">\r\n        <div class=\"container\">\r\n                            <header class=\"entry-header any-b0\">\r\n                                            <h5>Process<\/h5>\r\n                                                                <h2>Closed filling and storage process with AT-Closed Vial\u00ae<\/h2>\r\n                                    <\/header>\r\n                                        <div class=\"swiper process-element-slider\">\r\n                    <button class=\"swiper-button-prev\" type=\"button\">\r\n                        <span class=\"accessibility\">Previous slide<\/span>\r\n                        <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m9 17.003-8-8 8-8M1 9.003h21\" stroke=\"#004682\"\/><\/svg>\r\n                    <\/button>\r\n                    <ul class=\"swiper-wrapper list-reset\">\r\n                                                                                                                <li class=\"swiper-slide\">\r\n                                    <div class=\"process-element\">\r\n                                                                                    <div>\r\n                                                <span class=\"number\">1<\/span>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"any-b0\">\r\n                                                                                                    <h3>Vial provision<\/h3>\r\n                                                                                                <p>Vials are delivered pre-closed, gamma-sterilized, and ready to fill. Manufacturing and assembly take place under ISO 5 conditions, including comprehensive quality control and CCI verification.<\/p>\n                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/li>\r\n                                                                                                                                            <li class=\"swiper-slide\">\r\n                                    <div class=\"process-element\">\r\n                                                                                    <div>\r\n                                                <span class=\"number\">2<\/span>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"any-b0\">\r\n                                                                                                    <h3>Aseptic filling<\/h3>\r\n                                                                                                <p>The vial is punctured with a sterile needle through the stopper. Due to its elastic properties, the stopper reseals immediately. Airborne contamination is prevented as the system remains closed.<\/p>\n                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/li>\r\n                                                                                                                                            <li class=\"swiper-slide\">\r\n                                    <div class=\"process-element\">\r\n                                                                                    <div>\r\n                                                <span class=\"number\">3<\/span>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"any-b0\">\r\n                                                                                                    <h3>Laser re-sealing<\/h3>\r\n                                                                                                <p>The stopper is resealed using a one-second laser shot, restoring container closure integrity after puncturing. <\/p>\n                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/li>\r\n                                                                                                                                            <li class=\"swiper-slide\">\r\n                                    <div class=\"process-element\">\r\n                                                                                    <div>\r\n                                                <span class=\"number\">4<\/span>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"any-b0\">\r\n                                                                                                    <h3>Capping<\/h3>\r\n                                                                                                <p>A sterile snap cap is applied to secure the stopper until product use and protect against tampering.<\/p>\n                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/li>\r\n                                                                                                                                            <li class=\"swiper-slide\">\r\n                                    <div class=\"process-element\">\r\n                                                                                    <div>\r\n                                                <span class=\"number\">5<\/span>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"any-b0\">\r\n                                                                                                    <h3>Cryogenic storage<\/h3>\r\n                                                                                                <p>After filling, inspection, and labeling, the vials can be frozen (typically at -80 \u00b0C) and, if required, stored in liquid nitrogen (LN\u2082) before delivery to the clinical site.<\/p>\n                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/li>\r\n                                                                        <\/ul>\r\n                    <button class=\"swiper-button-next\" type=\"button\">\r\n                        <span class=\"accessibility\">Next slide<\/span>\r\n                        <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m13 17.003 8-8-8-8M21 9.003H0\" stroke=\"#004682\"\/><\/svg>\r\n                    <\/button>\r\n                    <nav class=\"swiper-pagination\"><\/nav>\r\n                <\/div>\r\n                    <\/div>\r\n    <\/section>\r\n\r\n\n\n    <section id=\"highlights\" class=\"section-column-element pt-default pb-default\">\r\n        <div class=\"container\">\r\n                            <header class=\"entry-header any-b0\">\r\n                                            <h5>Product highlights<\/h5>\r\n                                                                <h2>Comprehensive solution for aseptic filling<\/h2>\r\n                                    <\/header>\r\n                                        <ul class=\"column-element-list list-reset\">\r\n                                                                                                <li>\r\n                                <div class=\"column-element\">\r\n                                                                            <figure>\r\n                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized.jpg\" class=\"attachment-full size-full\" alt=\"Close-up of an automated mechanical gripper placing a pink cap onto a small glass vial in a sterile production environment.\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized-270x300.jpg 270w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized-922x1024.jpg 922w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized-768x853.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized-1382x1536.jpg 1382w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-capping-usp3_resized-357x397.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                        <\/figure>\r\n                                                                                                                <div class=\"body any-b0\">\r\n                                                                                            <h3>Uncompromising container closure integrity (CCI)<\/h3>\r\n                                                                                        <p>Validated CCI is ensured, which is critical for cryogenic storage. Robustness is achieved through vial design, polymer selection, ISO 5 assembly, and the closed filling method. The COC body and TPE stopper form a chemical bond, enhancing integrity at low temperatures. Validated methods such as dye ingress testing, CT scans, and laser-based headspace analysis confirm CCI.<\/p>\n                                        <\/div>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"column-element\">\r\n                                                                            <figure>\r\n                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize.jpg\" class=\"attachment-full size-full\" alt=\"A close-up of an automated filling needle piercing the blue stopper of a 1ml vial.\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize-270x300.jpg 270w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize-922x1024.jpg 922w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize-768x853.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize-1382x1536.jpg 1382w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/spectra-m1-vial-filling-close-up-usp1_Resize-357x397.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                        <\/figure>\r\n                                                                                                                <div class=\"body any-b0\">\r\n                                                                                            <h3>Risk reduction in aseptic filling<\/h3>\r\n                                                                                        <p>The functionally closed process eliminates airborne contamination risks. Unlike open vial methods, filling occurs through a resealable stopper, ensuring the vial remains closed at all times. This approach reduces product loss and significantly improves aseptic safety during filling and finishing.<\/p>\n                                        <\/div>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <div class=\"column-element\">\r\n                                                                            <figure>\r\n                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo.png 1404w, https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo-270x300.png 270w, https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo-922x1024.png 922w, https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo-768x853.png 768w, https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo-1382x1536.png 1382w, https:\/\/skan.com\/wp-content\/uploads\/2025\/05\/at-closed-vial-cryo-357x397.png 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                        <\/figure>\r\n                                                                                                                <div class=\"body any-b0\">\r\n                                                                                            <h3>Optimized for cryopreservation<\/h3>\r\n                                                                                        <p>Validated for long-term cryogenic storage at temperatures down to -196 \u00b0C. Polymer components with similar deformation behavior and the chemical bond between stopper and vial body ensure reliable integrity even under extreme conditions.<\/p>\n                                        <\/div>\r\n                                                                    <\/div>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n    <\/section>\r\n\r\n\r\n\n\n    <section id=\"regulatories\" class=\"section-image-text pt-default pb-default reverse default\">\r\n        <div class=\"container\">\r\n            <div class=\"entry-grid\">\r\n                                    <div class=\"text\">\r\n                        <div class=\"text-inner\">\r\n                                                            <h5>Regulatory requirements<\/h5>\r\n                                                                                        <h2>Highest regulatory standards<\/h2>\r\n                                                                                                                    <ul class=\"feature-list list-reset\">\r\n                                                                                                                                                                <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>Annex 1-compliant process design<\/h3>\n<p>The closed filling approach supports requirements for minimized interventions and reduced contamination risks.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                                                                                                                        <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>Container Closure Integrity (CCI)<\/h3>\n<p>Validated test methods (e.g., dye ingress, CT scan, headspace analysis) provide robust, regulatory- compliant proof of integrity.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                                                                                                                        <li>\r\n                                                <div class=\"feature-item\">\r\n                                                                                                                                                                <div class=\"any-b0\">\r\n                                                            <h3>Material compliance<\/h3>\n<p>All materials for the vials meet relevant requirements (USP\/EP) for primary packaging.<\/p>\n                                                        <\/div>\r\n                                                                                                    <\/div>\r\n                                            <\/li>\r\n                                                                                                            <\/ul>\r\n                                                                                <\/div>\r\n                    <\/div>\r\n                                                    <div class=\"image\">\r\n                        <figure class=\"\">\r\n                                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize-270x300.jpg 270w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize-922x1024.jpg 922w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize-768x853.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize-1382x1536.jpg 1382w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-application2_resize-357x397.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                                    <\/figure>\r\n                    <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/section>\r\n\n\n    <section id=\"specifications\" class=\"section-tabs-technical-information pt-default pb-default\">\r\n        <div class=\"container\">\r\n                            <h2>Technical specifications<\/h2>\r\n                                        <ul class=\"site-tablist\" data-tabs role=\"tablist\">\r\n                                                                    <li>\r\n                            <a href=\"#tab-Vials0block_64c78b0e378c93dc9ed5ff935ed81723\" data-tabby-default>Vials<\/a>\r\n                        <\/li>\r\n                                                                    <li>\r\n                            <a href=\"#tab-Packaging1block_64c78b0e378c93dc9ed5ff935ed81723\" >Packaging<\/a>\r\n                        <\/li>\r\n                                                                    <li>\r\n                            <a href=\"#tab-Extraction2block_64c78b0e378c93dc9ed5ff935ed81723\" >Extraction<\/a>\r\n                        <\/li>\r\n                                    <\/ul>\r\n                <div class=\"site-tab-content-wrap\">\r\n                                                                                                <div id=\"tab-Vials0block_64c78b0e378c93dc9ed5ff935ed81723\" class=\"tab-content any-b0\">\r\n                                                                                                    <ul class=\"technical-information-list list-reset\">\r\n                                                                                                                                                                                <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>Vial sizes<\/h5>\r\n                                                                                                                                                                            <p>1 ml, 2 ml, 6 ml, 10 ml, 20 ml, 50 ml<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                                                                                                                            <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>Filling volume<\/h5>\r\n                                                                                                                                                                            <p>0.1 ml to 45 ml<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                                                                                                                            <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>Materials<\/h5>\r\n                                                                                                                                                                            <p>COC (vial), TPE (stopper)<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                        <\/ul>\r\n                                                            <\/div>\r\n                                                                                                                        <div id=\"tab-Packaging1block_64c78b0e378c93dc9ed5ff935ed81723\" class=\"tab-content any-b0\">\r\n                                                                                                    <ul class=\"technical-information-list list-reset\">\r\n                                                                                                                                                                                <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>AT-CryoBox<\/h5>\r\n                                                                                                                                                                            <p>9-25 vials (cryogenic suitable)<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                                                                                                                            <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>AT-Nest<\/h5>\r\n                                                                                                                                                                            <p>25-88 vials<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                                                                                                                            <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>AT-Tray<\/h5>\r\n                                                                                                                                                                            <p>91-377 vials<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                        <\/ul>\r\n                                                            <\/div>\r\n                                                                                                                        <div id=\"tab-Extraction2block_64c78b0e378c93dc9ed5ff935ed81723\" class=\"tab-content any-b0\">\r\n                                                                                                    <ul class=\"technical-information-list list-reset\">\r\n                                                                                                                                                                                <li>\r\n                                                    <figure aria-hidden=\"true\">\r\n                                                                                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><rect x=\".5\" y=\".5\" width=\"23\" height=\"23\" rx=\"11.5\" fill=\"#E2ECF0\" stroke=\"#C5D9E1\"\/><path d=\"m7 11.73 3.5 3.77 6.5-7\" stroke=\"#004682\" stroke-width=\"1.5\" stroke-linecap=\"square\"\/><\/svg>\r\n                                                                                                            <\/figure>\r\n                                                    <div class=\"any-b0\">\r\n                                                                                                                    <h5>AT-Adapt<\/h5>\r\n                                                                                                                                                                            <p>Needle-free extraction for 2\u201350 ml vials<\/p>\r\n                                                                                                            <\/div>\r\n                                                <\/li>\r\n                                                                                                                        <\/ul>\r\n                                                            <\/div>\r\n                                                            <\/div>\r\n                    <\/div>\r\n    <\/section>\r\n\n\n    <section id=\"faqs\" class=\"section-download-accordions pt-default pb-default\">\r\n        <div class=\"container\">\r\n            <div class=\"entry-grid\">\r\n                <div class=\"any-b0\">\r\n                                            <h2>FAQs<\/h2>\r\n                                    <\/div>\r\n                                    <div>\r\n                                                    <ul class=\"site-accordion accordion list-reset\">\r\n                                                                                                                                                <li>\r\n                                            <button class=\"opener\" type=\"button\">\r\n                                                <span>What is the primary benefit of AT-Closed Vial\u00ae?<\/span>\r\n                                                <span class=\"icon\" aria-hidden=\"true\"><\/span>\r\n                                            <\/button>\r\n                                                                                            <div class=\"slide any-b0 has-custom-list\">\r\n                                                    <p>Reduction of contamination risks while maintaining validated container closure integrity \u2013 even under cryogenic conditions.<\/p>\n                                                <\/div>\r\n                                                                                    <\/li>\r\n                                                                                                                                                                                    <li>\r\n                                            <button class=\"opener\" type=\"button\">\r\n                                                <span>How is integrity ensured at cryogenic temperatures?<\/span>\r\n                                                <span class=\"icon\" aria-hidden=\"true\"><\/span>\r\n                                            <\/button>\r\n                                                                                            <div class=\"slide any-b0 has-custom-list\">\r\n                                                    <p>Through the combination of suitable polymer materials, chemical bonding between stopper and vial, and controlled ISO 5 manufacturing. Validated testing methods confirm tightness.<\/p>\n                                                <\/div>\r\n                                                                                    <\/li>\r\n                                                                                                                                                                                    <li>\r\n                                            <button class=\"opener\" type=\"button\">\r\n                                                <span>Is the filling system scalable?<\/span>\r\n                                                <span class=\"icon\" aria-hidden=\"true\"><\/span>\r\n                                            <\/button>\r\n                                                                                            <div class=\"slide any-b0 has-custom-list\">\r\n                                                    <p>Yes. It is compatible with AT filling solutions across different automation levels and can be used from development to commercial production.<\/p>\n                                                <\/div>\r\n                                                                                    <\/li>\r\n                                                                                                                                                                                    <li>\r\n                                            <button class=\"opener\" type=\"button\">\r\n                                                <span>How does the system differ from conventional glass vials?<\/span>\r\n                                                <span class=\"icon\" aria-hidden=\"true\"><\/span>\r\n                                            <\/button>\r\n                                                                                            <div class=\"slide any-b0 has-custom-list\">\r\n                                                    <p>Unlike open glass vial processes, the system remains closed during filling, significantly reducing contamination risks and improving cryogenic performance.<\/p>\n                                                <\/div>\r\n                                                                                    <\/li>\r\n                                                                                                <\/ul>\r\n                                            <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/section>\r\n\n\n    <section  class=\"section-download-accordions pt-default pb-default\">\r\n        <div class=\"container\">\r\n            <div class=\"entry-grid\">\r\n                <div class=\"any-b0\">\r\n                                            <h2>Download<\/h2>\r\n                                    <\/div>\r\n                                    <div>\r\n                                                    <ul class=\"download-list list-reset\">\r\n                                                                                                                                                <li>\r\n                                            <a class=\"download-item\" href=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/skan-AT-closed-vial-brochure.pdf\" download>\r\n                                                <span class=\"body\">\r\n                                                    <span class=\"name\">AT-Closed Vial\u00ae Ready-to-fill closed vial<\/span>\r\n                                                    <span class=\"info body-16\">\r\n                                                                                                                PDF 0.53 Mb\r\n                                                    <\/span>\r\n                                                <\/span>\r\n                                                <span class=\"icon\" aria-hidden=\"true\">\r\n                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M19 21H4V1h10l5 4.9V21Z\" stroke=\"#004682\"\/><path d=\"M14 1v5h5\" stroke=\"#004682\"\/><path d=\"M16 23a6 6 0 1 0 0-12 6 6 0 0 0 0 12Z\" fill=\"#C5D9E1\" stroke=\"#004682\"\/><path d=\"M16 14v5.5M18.5 17 16 19.5 13.5 17\" stroke=\"#004682\"\/><\/svg>\r\n                                                <\/span>\r\n                                            <\/a>\r\n                                        <\/li>\r\n                                                                                                <\/ul>\r\n                                            <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/section>\r\n\n\n    <section  class=\"section-product-teaser-slider pt-default pb-default\">\r\n        <div class=\"container\">\r\n                            <div class=\"entry-header any-b0\">\r\n                    <h2>Related products<\/h2>\r\n                <\/div>\r\n                    <\/div>\r\n        <div class=\"container\">\r\n                            <div class=\"swiper product-teaser-slider\">\r\n                    <button class=\"swiper-button-prev\" type=\"button\">\r\n                        <span class=\"accessibility\">Previous slide<\/span>\r\n                        <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m9 17.003-8-8 8-8M1 9.003h21\" stroke=\"#004682\"\/><\/svg>\r\n                    <\/button>\r\n                    <ul class=\"swiper-wrapper list-reset\">\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-46789 produkte type-produkte status-publish has-post-thumbnail hentry pharma-fill-finish-en pharma-drug-product-en pharma-atmp pharma-fill-finish-solutions\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/spectra-m1\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"spectra M1\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station-239x300.jpg 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station-817x1024.jpg 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station-768x963.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station-1225x1536.jpg 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/spectra-m1-integrated-filling-station-335x420.jpg 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Fill finish solutions<\/span>\r\n                                            <\/p>\r\n                                <h2>spectra M1<\/h2>\r\n                                    <p class=\"entry-excerpt\">Isolated fill and finish unit for small GMP batches<\/p>\r\n                                                    <dl class=\"product-attributes\">\r\n                                                                                                                <div>\r\n                                                                            <dt>Containers<\/dt>\r\n                                                                                                                <dd>AT-Closed Vial\u00ae<\/dd>\r\n                                                                    <\/div>\r\n                                                                                                                                                                            <div>\r\n                                                                            <dt>Objects per hour<\/dt>\r\n                                                                                                                <dd>Up to 150<\/dd>\r\n                                                                    <\/div>\r\n                                                    <\/dl>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-46786 produkte type-produkte status-publish has-post-thumbnail hentry pharma-fill-finish-en pharma-drug-product-en pharma-atmp pharma-fill-finish-solutions\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/pure2-m1\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"pure\u00b2 M1\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"Full view of the Pure2 M1 integrated small batch filling isolator, featuring a large central processing chamber with four glove ports, side pass-throughs, and an integrated control system in a cleanroom facility.\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize-239x300.jpg 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize-817x1024.jpg 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize-768x963.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize-1225x1536.jpg 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/pure2-m1-integrated-small-batch-filling-hero_resize-335x420.jpg 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Fill finish solutions<\/span>\r\n                                            <\/p>\r\n                                <h2>pure\u00b2 M1<\/h2>\r\n                                    <p class=\"entry-excerpt\">Getting started with isolator technology in the ATMP sector<\/p>\r\n                                                    <dl class=\"product-attributes\">\r\n                                                                                                                <div>\r\n                                                                            <dt>Containers<\/dt>\r\n                                                                                                                <dd>AT-Closed Vial\u00ae<\/dd>\r\n                                                                    <\/div>\r\n                                                                                                                                                                            <div>\r\n                                                                            <dt>Objects per hour<\/dt>\r\n                                                                                                                <dd>Up to 150<\/dd>\r\n                                                                    <\/div>\r\n                                                    <\/dl>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-53427 produkte type-produkte status-publish has-post-thumbnail hentry pharma-drug-product pharma-fill-finish-en pharma-drug-product-en pharma-atmp pharma-fill-finish-solutions\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/crystal-m1\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"Crystal M1\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"m1-small-batch-filling\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero-239x300.jpg 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero-817x1024.jpg 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero-768x963.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero-1225x1536.jpg 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/05\/m1-small-batch-filling-hero-335x420.jpg 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Fill finish solutions<\/span>\r\n                                            <\/p>\r\n                                <h2>Crystal M1<\/h2>\r\n                                    <p class=\"entry-excerpt\">Small batch aseptic filling station for the AT-Closed Vial\u00ae<\/p>\r\n                                                    <dl class=\"product-attributes\">\r\n                                                                                                                <div>\r\n                                                                            <dt>Containers<\/dt>\r\n                                                                                                                <dd>AT-Closed Vial\u00ae<\/dd>\r\n                                                                    <\/div>\r\n                                                                                                                                                                            <div>\r\n                                                                            <dt>Objects per hour<\/dt>\r\n                                                                                                                <dd>Up to 150<\/dd>\r\n                                                                    <\/div>\r\n                                                    <\/dl>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-46781 produkte type-produkte status-publish has-post-thumbnail hentry pharma-fill-finish-en pharma-drug-product pharma-drug-product-en pharma-atmp pharma-fill-finish-solutions\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/cellana-l1\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"Cellana L1\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize-270x300.jpg 270w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize-922x1024.jpg 922w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize-768x853.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize-1382x1536.jpg 1382w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-l1-automated-filling-laf-application_resize-357x397.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Fill finish solutions<\/span>\r\n                                            <\/p>\r\n                                <h2>Cellana L1<\/h2>\r\n                                    <p class=\"entry-excerpt\">Robotic fill finish line for the AT-Closed Vial\u00ae<\/p>\r\n                                                    <dl class=\"product-attributes\">\r\n                                                                                                                <div>\r\n                                                                            <dt>Containers<\/dt>\r\n                                                                                                                <dd>AT-Closed Vial\u00ae<\/dd>\r\n                                                                    <\/div>\r\n                                                                                                                                                                            <div>\r\n                                                                            <dt>Objects per hour<\/dt>\r\n                                                                                                                <dd>Up to 500<\/dd>\r\n                                                                    <\/div>\r\n                                                    <\/dl>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-52691 produkte type-produkte status-publish has-post-thumbnail hentry pharma-fill-finish-en pharma-drug-product-en pharma-atmp pharma-fill-finish-solutions\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/cellana-xl1\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"Cellana XL1\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc-239x300.jpg 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc-817x1024.jpg 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc-768x963.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc-1225x1536.jpg 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/cellana-xl1-automated-filling-ipc-335x420.jpg 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Fill finish solutions<\/span>\r\n                                            <\/p>\r\n                                <h2>Cellana XL1<\/h2>\r\n                                    <p class=\"entry-excerpt\">Robotic fill finish line for the AT-Closed Vial\u00ae with 100 % IPC<\/p>\r\n                                                    <dl class=\"product-attributes\">\r\n                                                                                                                <div>\r\n                                                                            <dt>Containers<\/dt>\r\n                                                                                                                <dd>AT-Closed Vial\u00ae <\/dd>\r\n                                                                    <\/div>\r\n                                                                                                                                                                            <div>\r\n                                                                            <dt>Objects per hour<\/dt>\r\n                                                                                                                <dd>Up to 700<\/dd>\r\n                                                                    <\/div>\r\n                                                    <\/dl>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-46587 produkte type-produkte status-publish has-post-thumbnail hentry pharma-drug-substance pharma-formulation pharma-transfer-drug-substance pharma-fill-finish-en pharma-transfer-drug-product pharma-drug-product-en pharma-atmp pharma-accessories-consumables pharma-filling-consumables pharma-commercial-production pharma-clinical-development\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/accessories\/single-use-systems\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"Single-use Systems\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web-239x300.jpg 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web-817x1024.jpg 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web-768x963.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web-1225x1536.jpg 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/single-use-assembly-custom-hero_web-335x420.jpg 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Accessories &amp; consumables, <\/span>\r\n                                                    <span>Filling consumables<\/span>\r\n                                            <\/p>\r\n                                <h2>Single-use Systems<\/h2>\r\n                                    <p class=\"entry-excerpt\">Custom single-use systems for sterile fluid transfer<\/p>\r\n                                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                    <li class=\"swiper-slide\">\r\n                                <article class=\"product-teaser post-46790 produkte type-produkte status-publish has-post-thumbnail hentry pharma-drug-substance pharma-upstream-downstream-subs pharma-formulation pharma-fill-finish-en pharma-transfer-drug-substance pharma-drug-product-en pharma-transfer-drug-product pharma-atmp pharma-accessories-consumables pharma-filling-consumables pharma-commercial-production pharma-clinical-development\">\r\n    <a href=\"https:\/\/skan.com\/en\/products\/pharma\/accessories\/clean-molded-parts\">\r\n        <figure class=\"entry-thumbnail\">\r\n            <div title=\"Clean molded parts\">\r\n                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1560\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing.jpg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing.jpg 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing-270x300.jpg 270w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing-922x1024.jpg 922w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing-768x853.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing-1382x1536.jpg 1382w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/clean-molded-parts-customized-tubing-357x397.jpg 357w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                            <\/div>\r\n                                <\/figure>\r\n        <div class=\"entry-body\">\r\n            <div class=\"inner\">\r\n                                    <p class=\"cats\">\r\n                                                    <span>Accessories &amp; consumables, <\/span>\r\n                                                    <span>Filling consumables<\/span>\r\n                                            <\/p>\r\n                                <h2>Clean molded parts<\/h2>\r\n                                    <p class=\"entry-excerpt\">Custom clean injection molding for pharma and life science applications<\/p>\r\n                                            <\/div>\r\n        <\/div>\r\n    <\/a>\r\n<\/article>                            <\/li>\r\n                                                                    <\/ul>\r\n                    <button class=\"swiper-button-next\" type=\"button\">\r\n                        <span class=\"accessibility\">Next slide<\/span>\r\n                        <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m13 17.003 8-8-8-8M21 9.003H0\" stroke=\"#004682\"\/><\/svg>\r\n                    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class=\"swiper-wrapper list-reset\">\r\n                                                            <li class=\"swiper-slide\">\r\n                                    <a class=\"icon-teaser-card adjustment\" href=\"https:\/\/skan.com\/en\/services\/pharma\/betrieb\/material-compatibility-tests\">\r\n    <div class=\"inner\">\r\n        <div class=\"head\">\r\n                            <figure class=\"icon\" aria-hidden=\"true\">\r\n                    <img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/03\/pikto-compatibility-tests.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                <\/figure>\r\n                                        <ul class=\"tag-topic-list list-reset\">\r\n                                                                                                <li>\r\n                                <span class=\"tag-topic\">\r\n                                    On-site                                <\/span>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <span class=\"tag-topic\">\r\n                                    At SKAN                                <\/span>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n        <h3>Material compatibility tests<\/h3>\r\n                    <p>Evaluation of material suitability for aseptic environments<\/p>\r\n                <span class=\"link\">\r\n            <span aria-hidden=\"true\"><\/span>\r\n            <span>Details<\/span>\r\n        <\/span>\r\n    <\/div>\r\n<\/a>                                <\/li>\r\n                                                            <li class=\"swiper-slide\">\r\n                                    <a class=\"icon-teaser-card adjustment\" href=\"https:\/\/skan.com\/en\/services\/pharma\/sterility-assurance\/h2o2-residue-check\">\r\n    <div class=\"inner\">\r\n        <div class=\"head\">\r\n                            <figure class=\"icon\" aria-hidden=\"true\">\r\n                    <img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/03\/pikto-h2o2-residue-check.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                <\/figure>\r\n                                        <ul class=\"tag-topic-list list-reset\">\r\n                                                                                                <li>\r\n                                <span class=\"tag-topic\">\r\n                                    At SKAN                                <\/span>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <span class=\"tag-topic\">\r\n                                    On-site                                <\/span>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n        <h3>H\u2082O\u2082 residue check<\/h3>\r\n                    <p>Identify risks posed by H\u2082O\u2082 residues early<\/p>\r\n                <span class=\"link\">\r\n            <span aria-hidden=\"true\"><\/span>\r\n            <span>Details<\/span>\r\n        <\/span>\r\n    <\/div>\r\n<\/a>                                <\/li>\r\n                                                            <li class=\"swiper-slide\">\r\n                                    <a class=\"icon-teaser-card adjustment\" href=\"https:\/\/skan.com\/en\/services\/pharma\/spare-parts\">\r\n    <div class=\"inner\">\r\n        <div class=\"head\">\r\n                            <figure class=\"icon\" aria-hidden=\"true\">\r\n                    <img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/02\/pikto-ersatzteile.svg\" class=\"attachment-full size-full\" alt=\"\" \/>                <\/figure>\r\n                                        <ul class=\"tag-topic-list list-reset\">\r\n                                                                                                <li>\r\n                                <span class=\"tag-topic\">\r\n                                    On-site                                <\/span>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n        <h3>Spare parts<\/h3>\r\n                    <p>Risk mitigation through reliable spare parts logistics<\/p>\r\n                <span class=\"link\">\r\n            <span aria-hidden=\"true\"><\/span>\r\n            <span>Details<\/span>\r\n        <\/span>\r\n    <\/div>\r\n<\/a> 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                         <\/li>\r\n                                                                                                                        <li>\r\n                                <span class=\"tag-topic\">\r\n                                    At SKAN                                <\/span>\r\n                            <\/li>\r\n                                                                                                                        <li>\r\n                                <span class=\"tag-topic\">\r\n                                    Digital                                <\/span>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                    <\/div>\r\n        <h3>SKAN Academy<\/h3>\r\n                    <p>Professional training program across the whole lifecycle<\/p>\r\n                <span class=\"link\">\r\n            <span aria-hidden=\"true\"><\/span>\r\n            <span>Details<\/span>\r\n        <\/span>\r\n    <\/div>\r\n<\/a>                                <\/li>\r\n                                                                                <\/ul>\r\n                        <button class=\"swiper-button-next\" type=\"button\">\r\n                            <span class=\"accessibility\">Next slide<\/span>\r\n                            <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m13 17.003 8-8-8-8M21 9.003H0\" stroke=\"#004682\"\/><\/svg>\r\n                        <\/button>\r\n                        <nav class=\"swiper-pagination\"><\/nav>\r\n                    <\/div>\r\n                                    <\/div>\r\n    <\/section>\r\n","protected":false},"author":4,"featured_media":51406,"parent":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"labor-reinraum":[],"pharma":[401,400,265,277,275],"class_list":["post-54091","produkte","type-produkte","status-publish","has-post-thumbnail","hentry","pharma-fill-finish-en","pharma-drug-product-en","pharma-atmp","pharma-accessories-consumables","pharma-filling-consumables"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>AT-Closed\u00a0Vial\u00ae - SKAN<\/title>\n<meta name=\"description\" content=\"A closed, ready-to-fill polymer vial system designed to enhance safety and reliability in aseptic filling and cryogenic storage.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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