{"id":53427,"date":"2025-06-02T09:52:00","date_gmt":"2025-06-02T07:52:00","guid":{"rendered":"https:\/\/skan.clients.ideeal.ch\/?post_type=produkte&p=53427"},"modified":"2026-05-13T21:45:03","modified_gmt":"2026-05-13T19:45:03","slug":"crystal-m1","status":"publish","type":"produkte","link":"https:\/\/skan.com\/en\/products\/pharma\/fill-finish\/crystal-m1","title":{"rendered":"Crystal M1"},"content":{"rendered":"
\r\n
\r\n
\r\n
Crystal M1 at a glance<\/h5>\r\n

Closed filling process for early-stage applications<\/h2>\r\n <\/header>\r\n
    \r\n
  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Closed vial processing<\/h3>\r\n

    AT-Closed Vial\u00ae enables a functionally closed filling process with minimal product exposure<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Annex 1 compliance<\/h3>\r\n

    Closed system design supports Annex 1 compliant aseptic processing<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Flexible barrier solution<\/h3>\r\n

    The system can be operated in a standard Biosafety Cabinet or an isolator<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Rapid deployment<\/h3>\r\n

    Installation and qualification within one day with minimal setup effort<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Single-use product path<\/h3>\r\n

    Disposable product contact parts eliminate cleaning requirements<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Versatility<\/h3>\r\n

    Supports all vial sizes from 1 ml to 50 ml for different applications<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Optimized for small batches<\/h3>\r\n

    Designed for low-volume production from a few up to several hundred vials<\/p>\r\n <\/div>\r\n <\/li>\r\n

  • \r\n
    \r\n
    \r\n <\/svg>\r\n <\/figure>\r\n

    Efficiency<\/h3>\r\n

    Quick, toolless format change and no additional utilities required<\/p>\r\n <\/div>\r\n <\/li>\r\n <\/ul>\r\n <\/div>\r\n <\/section>\r\n\r\n\n\n

    \r\n
    \r\n
    \r\n
    \r\n
    \r\n
    Application<\/h5>\r\n

    Closed aseptic filling for clinical and small-scale manufacturing<\/h2>\r\n
      \r\n
    • \r\n
      \r\n
      \r\n \"\" <\/figure>\r\n
      \r\n

      For cell and gene therapies<\/h3>\n

      Designed for personalized and high-value therapies with limited batch sizes.<\/p>\n <\/div>\r\n <\/div>\r\n <\/li>\r\n

    • \r\n
      \r\n
      \r\n \"\" <\/figure>\r\n
      \r\n

      For biologics and ATMPs<\/h3>\n

      Suitable for sensitive formulations, including next-generation biologics and innovative therapies.<\/p>\n <\/div>\r\n <\/div>\r\n <\/li>\r\n

    • \r\n
      \r\n
      \r\n \"\" <\/figure>\r\n
      \r\n

      For R&D and process development<\/h3>\n

      Provides a reproducible and validation-ready filling process for laboratory and pilot activities. Enables early definition of container strategy and simplifies future scale-up decisions.<\/p>\n <\/div>\r\n <\/div>\r\n <\/li>\r\n

    • \r\n
      \r\n
      \r\n \"Image <\/figure>\r\n
      \r\n

      For GMP compounding and hospital use<\/h3>\n

      Applicable for specialized compounding activities requiring high aseptic safety within compact and controlled environments.<\/p>\n <\/div>\r\n <\/div>\r\n <\/li>\r\n <\/ul>\r\n <\/div>\r\n <\/div>\r\n

      \r\n
      \r\n \"A <\/figure>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n <\/section>\r\n\n\n
      \r\n
      \r\n
      \r\n
      \r\n
      \r\n
      Fill Finish<\/h5>\r\n

      The AT-Closed Vial\u00ae ecosystem<\/h2>\r\n

      The AT-Closed Vial\u00ae system enables a fully closed aseptic filling process.<\/p>\n

      At its core is the AT-Closed Vial\u00ae as the primary packaging, combined with the AT-Cap as closure, complemented by suitable filling lines and the single-use system AT-Assembly for sterile liquid transfers.<\/p>\n

      All components are fully aligned, ensuring a consistent, contamination-controlled, and scalable process.<\/p>\n <\/div>\r\n <\/div>\r\n

      \r\n
      \r\n \"\" <\/figure>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n <\/section>\r\n\n\n
      \r\n
      \r\n
      \r\n
      Process<\/h5>\r\n

      The AT-Closed Vial\u00ae is filled in three simple steps<\/h2>\r\n <\/header>\r\n
      \r\n