{"id":54685,"date":"2026-04-21T16:42:09","date_gmt":"2026-04-21T14:42:09","guid":{"rendered":"https:\/\/skan.clients.ideeal.ch\/?post_type=expertise&#038;p=54685"},"modified":"2026-05-18T11:34:05","modified_gmt":"2026-05-18T09:34:05","slug":"the-collaboration-with-bio-manguinhos","status":"publish","type":"expertise","link":"https:\/\/skan.com\/en\/expertise\/pharma\/case-story\/partnership-biom","title":{"rendered":"The collaboration with Bio-Manguinhos"},"content":{"rendered":"\r\n        \r\n        \r\n            <section  class=\"section-post-hero\">\r\n            <div class=\"container\">\r\n                <div class=\"section-post-hero-grid\">\r\n                    <div class=\"section-post-hero-media\">\r\n                        <div class=\"entry-media\">\r\n                            \r\n                                <figure class=\"\">\r\n                                                                            <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process.png 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process-239x300.png 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process-817x1024.png 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process-768x963.png 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process-1225x1536.png 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-customized-isolator-formulation-process-335x420.png 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                                                    <\/figure>\r\n                        <\/div>\r\n                    <\/div>\r\n                    <div class=\"section-post-hero-text\">\r\n                                                <div class=\"limiter\">\r\n                                                            <h1>Partnership for global health<\/h1>\r\n                                                                                        <p>The collaboration with Bio-Manguinhos<\/p>\r\n                                                        <a class=\"link bottom anchor-link\" href=\"#nextSection\" role=\"button\">\r\n                                <span class=\"icon\"><span><span aria-hidden=\"true\"><\/span><\/span><\/span>\r\n                                <span class=\"text\">Learn more<\/span>\r\n                            <\/a>\r\n                        <\/div>\r\n                    <\/div>\r\n                <\/div>\r\n            <\/div>\r\n        <\/section>\r\n        <div aria-hidden=\"true\" id=\"nextSection\"><\/div>\r\n    \r\n    \r\n\n\n\t<section class=\"text-section\">\r\n\t\t<div id=\"intro\" class=\"section-main twocolumns-section pt-default pb-default\">\r\n\t\t\t<div class=\"container\">\r\n\t\t\t\t\t\t\t\t<div class=\"column-text half-width\">\r\n\t\t\t\t\t<h3>This story highlights a unique partnership with Bio-Manguinhos for a new facility at the Health Biotechnology Industrial Complex (CIBS) in Santa Cruz, Rio de Janeiro, Brazil.<\/h3>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/fiocruz.br\/en\" target=\"_blank\" rel=\"noopener\">Bio-Manguinhos<\/a> is one of 16 technical-scientific units of Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz), established in 1900. Fiocruz is a leading Brazilian research institution focused on health solutions, generating scientific and technological knowledge, and playing a vital role in health research and policy in Brazil.<\/p>\n<div class=\"block\">\n<p>Bio-Manguinhos\u00a0has been expanding its infrastructure and is set to operate a state-of-the-art plant in the Industrial District of Santa Cruz. The facility aims to increase the supply of vaccines and biopharmaceuticals for public health programs. It will house the Novo Centro de Processamento Final (NCPFI) \u2013 New Final Processing Center \u2013 along with dedicated quality assurance and control areas. The NCPFI handles the final steps in processing pharmaceutical products, such as packaging, quality control, and preparing the products for distribution or sale.<\/p>\n<p>The NCPFI project underscores Bio-Manguinhos\u2019 commitment to strengthening Brazil\u2019s health biotechnology sector by supporting global health initiatives. By adhering to key global regulatory standards (Anvisa, WHO, EMEA, and FDA), the project ensures that Bio-Manguinhos is well-positioned to operate within Brazil and globally, maintaining the highest quality standards.<\/p>\n<\/div>\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t<\/div>\r\n\t<\/section>\r\n\n\n\t<section  class=\"section-content pt-default pb-default\">\n\t\t<div class=\"container\">\n\t\t\t<div>\n\t\t\t\t\t\t\t\t\t<div class=\"block img-block\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"video-wrap img-wrap\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"vd\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1344\" height=\"720\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website.jpg\" class=\"attachment-full size-full\" alt=\"Employee of Bio-Manguinhos laughing in the camera.\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website.jpg 1344w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-300x161.jpg 300w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-1024x549.jpg 1024w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-768x411.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-357x191.jpg 357w\" sizes=\"auto, (max-width: 1344px) 100vw, 1344px\" \/>\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"vm\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1344\" height=\"720\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website.jpg\" class=\"attachment-full size-full\" alt=\"Employee of Bio-Manguinhos laughing in the camera.\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website.jpg 1344w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-300x161.jpg 300w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-1024x549.jpg 1024w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-768x411.jpg 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/bioM_thumbnail_website-357x191.jpg 357w\" sizes=\"auto, (max-width: 1344px) 100vw, 1344px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t                                                                                                        <div class=\"btn-wrap\">\n                                        <a\n                                            href=\"#block_739a4cc990ad13601ee729a8df8f78fc-1\"\n                                            data-fancybox=\"true\"\n                                            role=\"button\"\n                                        >\n                                            <svg width=\"140\" height=\"140\" viewBox=\"0 0 140 140\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                                <circle cx=\"70\" cy=\"70\" r=\"69.25\" stroke=\"#fff\" stroke-opacity=\".8\" stroke-width=\"1.5\"><\/circle>\n                                                <path d=\"m60 50 26 20-26 20V50Z\" fill=\"#fff\"><\/path>\n                                            <\/svg>\n                                        <\/a>\n                                    <\/div>\n                                    <div class=\"popup-video-holder\">\n                                        <div id=\"block_739a4cc990ad13601ee729a8df8f78fc-1\" class=\"ignite-video-popup\">\n                                            <div class=\"fancybox-content\">\n                                                <iframe class=\"fancybox-iframe\" title=\"Example Player Video\" src=\"https:\/\/skangroup.euvideocdn.com\/player\/index.html?id=69e785f9611c3fa3feba3ecf\" frameborder=\"0\" allowfullscreen style=\"border: none;\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write\"><\/iframe>\n                                            <\/div>\n                                        <\/div>\n                                    <\/div>\n                                \t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/section>\n\n\n\t<section class=\"text-section\">\r\n\t\t<div id=\"facility\" class=\"section-main twocolumns-section pt-default pb-default\">\r\n\t\t\t<div class=\"container\">\r\n\t\t\t\t\t\t\t\t<div class=\"column-text half-width\">\r\n\t\t\t\t\t<h3>Strengthening Vaccine Production<\/h3>\n<p>Brazil is facing an increasing national demand for vaccines. The NCPFI project is designed to meet this need while contributing to global health requirements. It will position Brazil as a significant player in the biopharmaceutical industry. The new campus in Santa Cruz spans over 580\u2019000 m\u00b2, with 334\u2019000 m\u00b2 dedicated to development. Once completed, the facility is expected to produce approximately 120 million vials annually.<\/p>\n<h3>State-of-the-Art Manufacturing Facility<\/h3>\n<p>The NCPFI project, initiated in 2011 and officially started in 2017, involved extensive groundwork, including soil testing, environmental licensing, and equipment procurement. Major construction is ongoing, and key equipment like filling lines and lyophilizers has already been secured.<\/p>\n<p>The facility will feature four isolator filling lines, three with integrated lyophilizers and one dedicated exclusively to liquids. These four state-of-the-art production lines provide a reliable basis for high-volume and high-precision manufacturing. Additional process equipment like formulation isolators, sterility test isolators, and downflow booths complete the facility\u2019s holistic approach. The layout is optimized to enhance productivity and maintain strict safety standards.<\/p>\n<h3>Setting New Standards<\/h3>\n<p>Moreover, the NCPFI will be a global showcase for pioneering aseptic process applications. This includes the introduction of customized isolators for formulation processes. This application remains rare in the industry but will become increasingly the preferred choice for the future of biopharmaceutical production. By implementing these advanced systems, Bio-Manguinhos is not only enhancing its capabilities but is also setting a new global benchmark for even safer biopharmaceutical manufacturing.<\/p>\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t<\/div>\r\n\t<\/section>\r\n\n\n\n\n    <section id=\"related\" class=\"section-case-stories-slider pt-default pb-default\">\r\n                    <header class=\"entry-header text-blue\">\r\n                <div class=\"container\">\r\n                                            <h2>To the next case story:<\/h2>\r\n                                                        <\/div>\r\n            <\/header>\r\n                            <div class=\"case-stories-slider swiper\">\r\n                <button class=\"swiper-button-prev\" type=\"button\">\r\n                    <span class=\"accessibility\">Previous slide<\/span>\r\n                    <svg aria-hidden=\"true\" width=\"22\" height=\"18\" viewBox=\"0 0 22 18\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m9 17.003-8-8 8-8M1 9.003h21\" stroke=\"#004682\"\/><\/svg>\r\n                <\/button>\r\n                <ul class=\"swiper-wrapper\">\r\n                                                                                                <li class=\"swiper-slide\">\r\n                                <article class=\"case-stories-card bg-light\">\r\n                                    <div class=\"container\">\r\n                                                                                    <div class=\"entry-thumbnail\">\r\n                                                <figure>\r\n                                                    <img loading=\"lazy\" decoding=\"async\" width=\"1404\" height=\"1760\" src=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators.png 1404w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators-239x300.png 239w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators-817x1024.png 817w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators-768x963.png 768w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators-1225x1536.png 1225w, https:\/\/skan.com\/wp-content\/uploads\/2026\/04\/skan-case-story-BioM-Video-pharmaceutical-formulation-isolators-335x420.png 335w\" sizes=\"auto, (max-width: 1404px) 100vw, 1404px\" \/>                                                <\/figure>\r\n                                            <\/div>\r\n                                                                                                                            <div class=\"entry-body\">\r\n                                                                                                                                                    <h2>Isolator technology for pharmaceutical formulation<\/h2>\r\n                                                                                                <p>The isolator was designed with specific applications in mind, tailored to meet the unique needs of Bio-Manguinhos\u2019 formulation processes.<\/p>\n                                                                                                    <a\r\n                                                        class=\"link\"\r\n                                                        href=\"https:\/\/skan.com\/en\/expertise\/pharma\/case-story\/isolator-technology-pharmaceutical-formulation\"\r\n                                                        target=\"_self\"\r\n                                                        role=\"button\"\r\n                                                    >\r\n                                                        <span aria-hidden=\"true\"><\/span>\r\n                                                        <span>Read more<\/span>\r\n                                                    <\/a>\r\n                                                                                                                                            <\/div>\r\n                                                                            <\/div>\r\n                                <\/article>\r\n                            <\/li>\r\n                                                            <\/ul>\r\n                <button class=\"swiper-button-next\" type=\"button\">\r\n                    <span class=\"accessibility\">Next slide<\/span>\r\n                    <svg aria-hidden=\"true\" width=\"22\" 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